Amino 5-HTP | CR-60
Amino 5-HTP | CR-60
Clinical Applications
• Supports Healthy Biosynthesis of Serotonin
• Supports Healthy Mood and Positive Outlook
• Supports Normal Appetite
• Supports Restful Sleep Pattern
Amino 5-HTP | CR-60 has a delivery system that releases 5-HTP slowly and steadily over a period of time. 5-HTP is a drug-free amino acid derived from a plant that naturally increases the body’s level of serotonin, the chemical messenger that affects emotions, behavior, appetite, and sleep. Today’s stress-filled lifestyles and dietary practices may negatively affect how the body handles serotonin. Regular use of Cell FusioNX’s Amino 5-HTP | CR-60 helps promote a more positive outlook and greater appetite control.*
Discussion
5-hydroxytryptophan (5-HTP) is a precursor to serotonin. In the body, the essential amino acid tryptophan
(when acted upon by the enzyme tryptophan hydroxylase) converts to 5-HTP. The compound is subsequently
decarboxylated to serotonin, thereby elevating extracellular serum serotonin levels. Supplementing with 5-HTP
bypasses the somewhat limiting conversion of tryptophan to 5-HTP.[1,2] Oral 5-HTP is well-absorbed in the
intestine without the need for a transporter; other amino acids do not compete with it for absorption. It easily
crosses the blood-brain barrier, is not degraded by the enzymes that degrade tryptophan, and it is excreted
through the kidneys.*[1,3]
Mood and Comfort Serotonin regulates many normal brain activities, increases norepinephrine and dopamine,
and is important in regulating mood and behavior. Adequate levels of serotonin are associated with normal
calmness and relaxation.*[1-5]
Several studies have demonstrated that 5-HTP supports a healthy frame of mind, good energy levels, ease
of movement, and restful sleep.[1,6,7] Published studies (dose~100-600 mg/day) have also demonstrated the
effectiveness of 5-HTP supplementation in supporting cerebral comfort.*[8-10]
Appetite Used in a high dose (i.e., 300 mg/three times a day), 5-HTP decreased food consumption and
reduced weight. This result may relate to the effect of 5-HTP in supporting normal hypothalamic regulation,
which includes appetite homeostasis.[11] However, nausea at this relatively high dose was a common complaint.
[12,13] In other research, sublingual 5-HTP administered five times per day for eight weeks in adult overweight
women significantly supported feelings of post-meal hunger satisfaction.*[14]
Hormones and Sleep 5-HTP is thought to effect the HPA axis, as it has the ability to raise plasma cortisol
levels, to cause transient increase in growth hormone (at 150 mg dose), and in men only, to support healthy
levels of thyroid stimulating hormone.[15,16] Serotonin is also converted to melatonin; thus, supplementation has
similar effects. Support of sleep quality is likely related to 5-HTP’s ability to increase the length of rapid eye
movement (REM).[3,17] In children, supplementation with 5-HTP may help modulate arousal level and support
peaceful sleep.*[18]
